nwliu/EvoLlama

Model

EvoLlama

0

3 commits

3 linked in READMEs

updated Mar 14, 2025

See the code

README

EvoLlama

EvoLlama is a multimodal framework that connects a structure-based protein encoder, a sequence-based protein encoder, and an LLM for protein understanding through a two-stage training process. For more details, please refer to our paper: EvoLlama: Enhancing LLMs' Understanding of Proteins via Multimodal Structure and Sequence Representations.

Quickstart

For more details, please refer to our GitHub repository.

Model Family

ModelsStagesDatasetsPDBPaths
EvoLlama (ProteinMPNN + ESM-2)Projection TuningSwissProtAlphaFold-2projection_tuning/protein_mpnn_esm2_650m
EvoLlama (ProteinMPNN + ESM-2)Supervised Fine-tuningPMol + PEERESMFoldsupervised_fine_tuning/protein_mpnn_esm2_650m
EvoLlama (GearNet + ESM-2)Projection TuningSwissProtAlphaFold-2Coming soon ...
EvoLlama (GearNet + ESM-2)Supervised Fine-tuningPMol + PEERESMFoldComing soon ...

Model Architecture

EvoLlama is initialized with the weights of the following models:

ModelsLinks
ProteinMPNNLink
GearNetLink
ESM-2 650M (facebook/esm2_t33_650M_UR50D)Link
Llama-3 (meta-llama/Meta-Llama-3-8B-Instruct)Link

Citation

@misc{liu2024evollama,
    title={EvoLlama: Enhancing LLMs' Understanding of Proteins via Multimodal Structure and Sequence Representations}, 
    author={Nuowei Liu and Changzhi Sun and Tao Ji and Junfeng Tian and Jianxin Tang and Yuanbin Wu and Man Lan},
    year={2024},
    eprint={2412.11618},
    archivePrefix={arXiv},
    primaryClass={cs.LG},
    url={https://arxiv.org/abs/2412.11618}, 
}
safetensors

Contributors

nwliu

3 commits

nwliu/EvoLlama

Model

EvoLlama

0

3 commits

3 linked in READMEs

updated Mar 14, 2025

See the code

README

EvoLlama

EvoLlama is a multimodal framework that connects a structure-based protein encoder, a sequence-based protein encoder, and an LLM for protein understanding through a two-stage training process. For more details, please refer to our paper: EvoLlama: Enhancing LLMs' Understanding of Proteins via Multimodal Structure and Sequence Representations.

Quickstart

For more details, please refer to our GitHub repository.

Model Family

ModelsStagesDatasetsPDBPaths
EvoLlama (ProteinMPNN + ESM-2)Projection TuningSwissProtAlphaFold-2projection_tuning/protein_mpnn_esm2_650m
EvoLlama (ProteinMPNN + ESM-2)Supervised Fine-tuningPMol + PEERESMFoldsupervised_fine_tuning/protein_mpnn_esm2_650m
EvoLlama (GearNet + ESM-2)Projection TuningSwissProtAlphaFold-2Coming soon ...
EvoLlama (GearNet + ESM-2)Supervised Fine-tuningPMol + PEERESMFoldComing soon ...

Model Architecture

EvoLlama is initialized with the weights of the following models:

ModelsLinks
ProteinMPNNLink
GearNetLink
ESM-2 650M (facebook/esm2_t33_650M_UR50D)Link
Llama-3 (meta-llama/Meta-Llama-3-8B-Instruct)Link

Citation

@misc{liu2024evollama,
    title={EvoLlama: Enhancing LLMs' Understanding of Proteins via Multimodal Structure and Sequence Representations}, 
    author={Nuowei Liu and Changzhi Sun and Tao Ji and Junfeng Tian and Jianxin Tang and Yuanbin Wu and Man Lan},
    year={2024},
    eprint={2412.11618},
    archivePrefix={arXiv},
    primaryClass={cs.LG},
    url={https://arxiv.org/abs/2412.11618}, 
}
safetensors

Contributors

nwliu

3 commits